Hepatoprotective and antioxidant activity of Murraya Koenigii leaves extract against paracetamol induced hepatotoxicity in Rats
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منابع مشابه
Hepatoprotective Activity of Methanol Extract of Tecomella undulata against Alcohol and Paracetamol Induced Hepatotoxicity in Rats
Plant products play a crucial role in the hepatoprotection through its antioxidants property. Therefore, search for modern medicine of plant origin with this property has become a central focus on hepatoprotection today. This study investigated to search a new hepatoprotective agent from natural sources, the methanol extract of folk medicinal plant, T. undulata leaves was tested against liver d...
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Objectives: Aim of the study is to find therapeutic potentials of aqueous Curry Leaf (Murraya koenigii) Extract (CuLE) against lead induced oxidative damage in hepatic tissue. The objectives are to study the alterations of various stress parameters in lead induced hepatotoxicity and amelioration of the same with CuLE. Methods: Rats were intraperitoneally injected with lead acetate (15mg/kg body...
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Objective: Ethanol extract of Cajanus cajan (L.) Millsp. (Pigeonpea) leaves (ECC) was investigated for its hepatoprotective activity. Methods: Different groups of Wistar albino rats were administered with paracetamol (500 mg/kg, p.o., once daily for 7 days) for induction of hepatotoxicity. ECC (100, 200 and 300 mg/kg/day) and silymarin (25 mg/kg/day) were administered to the paracetamol induced...
متن کاملHepatoprotective Activity of Methanolic Extract of Bauhinia purpurea Leaves against Paracetamol-Induced Hepatic Damage in Rats
In an attempt to further establish the pharmacological properties of Bauhinia purpurea (Fabaceae), hepatoprotective potential of methanol extract of B. purpurea leaves (MEBP) was investigated using the paracetamol- (PCM-) induced liver toxicity in rats. Five groups of rats (n = 6) were used and administered orally once daily with 10% DMSO (negative control), 200 mg/kg silymarin (positive contro...
متن کاملIn vitro antioxidant activity and hepatoprotective effects of Lentinula edodes against paracetamol-induced hepatotoxicity.
BACKGROUND The objective of this study was to investigate the antioxidant and hepatoprotective effects of methanolic extracts of L. edodes and the determination of their total phenolics content. RESULTS The amount of total phenolics was estimated to be 70.83 mg Gallic Acid Equivalent (GAE) per gram of dry extract. The antioxidant activity of the L. edodes extract was 39.0% at a concentration ...
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ژورنال
عنوان ژورنال: International Journal of Basic & Clinical Pharmacology
سال: 2017
ISSN: 2279-0780,2319-2003
DOI: 10.18203/2319-2003.ijbcp20172044